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› 7ysp

Electron Microscopy
3.9Å resolution

Tubulin heterodimer structure of GDP-2 state in solution

Released:
DOI: 10.2210/pdb7ysp/pdb
PDB entry 7ysp coloured by chain, front view.
PDB entry 7ysp coloured by chain, side view.
PDB entry 7ysp coloured by chain, top view.
Source organism: Sus scrofa
Primary publication:
Structural insights into the mechanism of GTP initiation of microtubule assembly.
Zhou J, Wang A, Song Y, Liu N, Wang J, Li Y, Liang X, Li G, Chu H, Wang HW
OpenAccess logo Nat Commun 14 5980 (2023)
PMID: 37749104
Related structures: EMD-34079

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-232418 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Tubulin alpha-1B chain Chain: A
Molecule details ›
Chain: A
Length: 451 amino acids
Theoretical weight: 50.2 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: Q2XVP4 (Residues: 1-451; Coverage: 100%)
Gene name: TUBA1B
Sequence domains:
Tubulin beta chain Chain: B
Molecule details ›
Chain: B
Length: 445 amino acids
Theoretical weight: 49.91 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: P02554 (Residues: 1-445; Coverage: 100%)
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand GTP 1 x GTP
Ligand GDP 1 x GDP
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 3.9Å
Relevant EMDB volumes: EMD-34079

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