› 7yvt

X-ray diffraction
2.38Å resolution

S-formylglutathione hydrolase from Variovorax sp. PAMC 28711

Released:
DOI: 10.2210/pdb7yvt/pdb
PDB entry 7yvt coloured by chain, front view.
PDB entry 7yvt coloured by chain, side view.
PDB entry 7yvt coloured by chain, top view.
Source organism: Variovorax sp.
Primary publication:
Structural basis for the substrate specificity of an S-formylglutathione hydrolase derived from Variovorax sp. PAMC 28711.
Hwang J, Kim B, Lee MJ, Nam Y, Youn UJ, Lee CS, Oh TJ, Park HH, Do H, Lee JH
Biochem Biophys Res Commun 629 159-164 (2022)
PMID: 36122453

Function and Biology Details

Reaction catalysed: 
S-formylglutathione + H(2)O = glutathione + formate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-102892 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
S-formylglutathione hydrolase Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 295 amino acids
Theoretical weight: 32.1 KDa
Source organism: Variovorax sp.
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A126ZFJ3 (Residues: 1-295; Coverage: 100%)
Gene name: AX767_16275
Sequence domains: Putative esterase

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 5C (4A)
Spacegroup: C2
Unit cell:
a: 53.204Å b: 76.437Å c: 199.865Å
α: 90° β: 91.192° γ: 90°
R-values:
R R work R free
0.206 0.204 0.245
Expression system: Escherichia coli

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