7zak

X-ray diffraction
1.62Å resolution

Crystal structure of HLA-DP (DPA1*02:01-DPB1*01:01) in complex with a peptide

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-169177 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
MHC class II HLA-DP alpha chain (DPA1*02:01) Chain: A
Molecule details ›
Chain: A
Length: 268 amino acids
Theoretical weight: 29.81 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
MHC class II HLA-DP beta chain (DPB1*01:01) Chain: B
Molecule details ›
Chain: B
Length: 262 amino acids
Theoretical weight: 29.73 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
Synthetic peptide Chain: C
Molecule details ›
Chain: C
Length: 15 amino acids
Theoretical weight: 1.87 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P212121
Unit cell:
a: 54Å b: 82.682Å c: 105.977Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.207 0.205 0.23
Expression systems:
  • Drosophila melanogaster
  • Not provided