› 7znf

Solution NMR

ALTERNATING ZINC FINGERS IN THE HUMAN MALE ASSOCIATED PROTEIN ZFY: 2D NMR STRUCTURE OF AN EVEN FINGER AND IMPLICATIONS FOR "JUMPING-LINKER" DNA RECOGNITION

Released:
DOI: 10.2210/pdb7znf/pdb
PDB entry 7znf coloured by chain, ensemble of 12 models, front view.
PDB entry 7znf coloured by chain, ensemble of 12 models, side view.
PDB entry 7znf coloured by chain, ensemble of 12 models, top view.
Source organism: Homo sapiens
Primary publication:
Alternating zinc fingers in the human male associated protein ZFY: 2D NMR structure of an even finger and implications for "jumping-linker" DNA recognition.
Kochoyan M, Havel TF, Nguyen DT, Dahl CE, Keutmann HT, Weiss MA
Biochemistry 30 3371-86 (1991)
PMID: 1849423

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139898 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Zinc finger Y-chromosomal protein Chain: A
Molecule details ›
Chain: A
Length: 30 amino acids
Theoretical weight: 3.64 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P08048 (Residues: 570-598; Coverage: 4%)
Gene name: ZFY
Sequence domains: C2H2-type zinc-finger domain

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

2 review citations

Regulation of transcription in eukaryotes by DNA-binding proteins.
Krajewska WM. (1992)
1 more

4 mentions without citation

The oncoprotein EVI1 and the DNA methyltransferase Dnmt3 co-operate in binding and de novo methylation of target DNA.
Senyuk et al. (2011)
3 more