Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- SH2 domain
- SH2 domain superfamily
- STAT transcription factor, protein interaction
- STAT transcription factor, N-terminal domain superfamily
- WD40/YVTN repeat-like-containing domain superfamily
- Signal transducer and activation of transcription 2, C-terminal
- STAT2, SH2 domain
- Signal transducer and activator of transcription, linker domain
11 more domains
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-125631 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
DNA damage-binding protein 1
Molecule details ›
Chain: A
Length: 840 amino acids
Theoretical weight: 93.67 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Length: 840 amino acids
Theoretical weight: 93.67 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
Q16531 (Residues: 1-396, 706-1140; Coverage: 73%) - Best match: Q16531-2 (Residues: 59-451)
Sequence domains:
B27a
Molecule details ›
Chain: B
Length: 659 amino acids
Theoretical weight: 76.34 KDa
Source organism: Murid betaherpesvirus 8
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Herpesvirus U5-like family
Length: 659 amino acids
Theoretical weight: 76.34 KDa
Source organism: Murid betaherpesvirus 8
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: K7Y9Z1 (Residues: 1-656; Coverage: 100%)
Sequence domains: Herpesvirus U5-like family
Signal transducer and activator of transcription
