7zxu

X-ray diffraction
1.89Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-225291 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Spike protein S1 Chain: E
Molecule details ›
Chain: E
Length: 202 amino acids
Theoretical weight: 23 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 333-528; Coverage: 16%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
Nanobody C1 Chain: A
Molecule details ›
Chain: A
Length: 131 amino acids
Theoretical weight: 14.66 KDa
Source organism: Lama glama
Expression system: Escherichia coli
Beta-27 heavy chain Chain: H
Molecule details ›
Chain: H
Length: 222 amino acids
Theoretical weight: 23.53 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Beta-27 light chain Chain: L
Molecule details ›
Chain: L
Length: 214 amino acids
Theoretical weight: 23.13 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P212121
Unit cell:
a: 84.106Å b: 100.436Å c: 105.443Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.182 0.181 0.209
Expression systems:
  • Homo sapiens
  • Escherichia coli