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› 8b55

X-ray diffraction
1.36Å resolution

Human ADGRG4 PTX-like domain

Released:
DOI: 10.2210/pdb8b55/pdb
Model geometry
Fit model/data
PDB entry 8b55 coloured by chain, front view.
PDB entry 8b55 coloured by chain, side view.
PDB entry 8b55 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The dimerized pentraxin-like domain of the adhesion G protein-coupled receptor 112 (ADGRG4) suggests function in sensing mechanical forces.
Kieslich B, Weiße RH, Brendler J, Ricken A, Schöneberg T, Sträter N
OpenAccess logo J Biol Chem 299 105356 (2023)
PMID: 37863265

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-275137 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adhesion G-protein coupled receptor G4, N-terminal fragment Chain: A
Molecule details ›
Chain: A
Length: 239 amino acids
Theoretical weight: 27.45 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q8IZF6 (Residues: 26-240; Coverage: 7%)
Gene names: ADGRG4, GPR112
Sequence domains: Pentaxin family

Ligands and Environments

1 bound ligand:
Ligand MG 1 x MG
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: PETRA III, EMBL c/o DESY BEAMLINE P14 (MX2)
Spacegroup: C2
Unit cell:
a: 113.117Å b: 40.243Å c: 54.912Å
α: 90° β: 113.9° γ: 90°
R-values:
R R work R free
0.157 0.154 0.189
Expression system: Homo sapiens

Quick links

Citations

1 mention without citation

The dimerized pentraxin-like domain of the adhesion G protein-coupled receptor 112 (ADGRG4) suggests function in sensing mechanical forces.
Kieslich et al. (2023)