8bpo

Electron Microscopy
2.8Å resolution

Structure of rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 (TTC5) and S-phase Cyclin A Associated Protein residing in the ER (SCAPER)

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero 51-mer (preferred)
PDBe Complex ID:
PDB-CPX-292002 (preferred)
Entry contents:
48 distinct polypeptide molecules
3 distinct RNA molecules
Macromolecules (51 distinct):
Nascent polypeptide-associated complex subunit alpha N-terminal region Chain: D1
Molecule details ›
Chain: D1
Length: 29 amino acids
Theoretical weight: 2.53 KDa
Source organism: Oryctolagus cuniculus
60S ribosomal protein L8 Chain: A2
Molecule details ›
Chain: A2
Length: 257 amino acids
Theoretical weight: 28.09 KDa
Source organism: Oryctolagus cuniculus
Large ribosomal subunit protein uL3 Chain: B2
Large ribosomal subunit protein uL4 Chain: C2
Large ribosomal subunit protein uL18 Chain: D2
Large ribosomal subunit protein eL6 Chain: E2
60S ribosomal protein L7 Chain: F2
Large ribosomal subunit protein eL8 Chain: G2
Large ribosomal subunit protein uL6 Chain: H2
Large ribosomal subunit protein uL16 Chain: I2
Large ribosomal subunit protein uL5 Chain: J2
Large ribosomal subunit protein eL13 Chain: K2
Large ribosomal subunit protein eL14 Chain: L2
Large ribosomal subunit protein eL15 Chain: M2
60S ribosomal protein L13a Chain: N2
60S ribosomal protein L17 Chain: O2
Ribosomal protein L18 Chain: P2
60S ribosomal protein L19 Chain: Q2
60S ribosomal protein L18a Chain: R2
Large ribosomal subunit protein eL21 Chain: S2
60S ribosomal protein L22 Chain: T2
Large ribosomal subunit protein uL14 Chain: U2
Large ribosomal subunit protein eL24 Chain: V2
Large ribosomal subunit protein uL23 Chain: W2
Large ribosomal subunit protein uL24 Chain: X2
Large ribosomal subunit protein eL27 Chain: Y2
Large ribosomal subunit protein uL15 Chain: Z2
Large ribosomal subunit protein eL29 Chain: a2
Large ribosomal subunit protein eL30 Chain: b2
Large ribosomal subunit protein eL31 Chain: c2
Large ribosomal subunit protein eL32 Chain: d2
Large ribosomal subunit protein eL33 Chain: e2
Large ribosomal subunit protein eL34 Chain: f2
Large ribosomal subunit protein uL29 Chain: g2
Large ribosomal subunit protein eL36 Chain: h2
Large ribosomal subunit protein eL37 Chain: i2
Large ribosomal subunit protein eL38 Chain: j2
Large ribosomal subunit protein eL39 Chain: k2
Ubiquitin-60S ribosomal protein L40 Chain: l2
Small ribosomal subunit protein eS32 Chain: m2
Large ribosomal subunit protein eL42 Chain: n2
Large ribosomal subunit protein eL43 Chain: o2
Large ribosomal subunit protein eL28 Chain: p2
Large ribosomal subunit protein uL10 Chain: q2
Large ribosomal subunit protein uL11 Chain: r2
S phase cyclin A-associated protein in the endoplasmic reticulum Chain: s2
Tetratricopeptide repeat protein 5 Chain: t2
Tubulin beta chain Chain: u2
28S ribosomal RNA Chain: A1
5S ribosomal RNA Chain: B1
5.8S ribosomal RNA Chain: C1

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 2.8Å
Relevant EMDB volumes: EMD-16155
Expression systems:
  • Homo sapiens
  • Escherichia coli
  • Oryctolagus cuniculus