› 8bw6

X-ray diffraction
1.95Å resolution

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186809 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Titin Chain: A
Molecule details ›
Chain: A
Length: 99 amino acids
Theoretical weight: 11.04 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8WZ42 (Residues: 14415-14509; Coverage: 0%)
Gene name: TTN
Sequence domains: Fibronectin type III domain

Ligands and Environments

3 bound ligands:
Ligand EDO 7 x EDO
Ligand PEG 1 x PEG
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P41212
Unit cell:
a: 45.86Å b: 45.86Å c: 112.02Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.219 0.217 0.254
Expression system: Escherichia coli

Quick links

Citations

1 citations in other articles

Molecular insights into titin's A-band.
Fleming et al. (2023)

1 mention without citation

Immunological and Structural Characterization of Titin Main Immunogenic Region; I110 Domain Is the Target of Titin Antibodies in Myasthenia Gravis.
Stergiou et al. (2023)