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8c7g

Electron Microscopy
3.2Å resolution

Drosophila melanogaster Rab7 GEF complex Mon1-Ccz1-Bulli

Released:
Source organism: Drosophila melanogaster
Primary publication:
Structure of the metazoan Rab7 GEF complex Mon1-Ccz1-Bulli.
OpenAccess logo Proc Natl Acad Sci U S A 120 e2301908120 (2023)
PMID: 37155863
Related structures: EMD-16457

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-216065 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Regulator of MON1-CCZ1 complex Chain: A
Molecule details ›
Chain: A
Length: 642 amino acids
Theoretical weight: 72.06 KDa
Source organism: Drosophila melanogaster
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9VRX1 (Residues: 1-642; Coverage: 100%)
Gene names: Bulli, CG8270
Sequence domains:
Vacuolar fusion protein CCZ1 homolog Chain: B
Molecule details ›
Chain: B
Length: 507 amino acids
Theoretical weight: 58.31 KDa
Source organism: Drosophila melanogaster
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9VZL5 (Residues: 1-485; Coverage: 100%)
Gene names: CG14980, Ccz1
Sequence domains:
Vacuolar fusion protein MON1 homolog Chain: C

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 3.2Å
Relevant EMDB volumes: EMD-16457
Expression system: Spodoptera frugiperda