Function and Biology Details
Reactions catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
ATP + H(2)O = ADP + phosphate
Peptidylproline (omega=180) = peptidylproline (omega=0)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero 59-mer (preferred)
PDBe Complex ID:
PDB-CPX-301284 (preferred)
Entry contents:
45 distinct polypeptide molecules
4 distinct RNA molecules
4 distinct RNA molecules
Macromolecules (49 distinct):
Small nuclear ribonucleoprotein E
Molecule details ›
Chains: 1, i
Length: 92 amino acids
Theoretical weight: 10.82 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: LSM domain
Length: 92 amino acids
Theoretical weight: 10.82 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P62304 (Residues: 1-92; Coverage: 100%)
Sequence domains: LSM domain
Small nuclear ribonucleoprotein F
Molecule details ›
Chains: 2, h
Length: 86 amino acids
Theoretical weight: 9.73 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: LSM domain
Length: 86 amino acids
Theoretical weight: 9.73 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62306 (Residues: 1-86; Coverage: 100%)
Sequence domains: LSM domain
Small nuclear ribonucleoprotein Sm D3
Small nuclear ribonucleoprotein Sm D2
Small nuclear ribonucleoprotein Sm D1
Small nuclear ribonucleoprotein-associated proteins B and B'
Small nuclear ribonucleoprotein G
Splicing factor 3B subunit 3
Splicing factor 3B subunit 5
Splicing factor 3B subunit 1
PHD finger-like domain-containing protein 5A
Splicing factor 3B subunit 2
Splicing factor 3B subunit 4
G-patch domain and KOW motifs-containing protein
Splicing factor 3A subunit 1
Splicing factor 3A subunit 2
Splicing factor 3A subunit 3
Pre-mRNA-processing factor 19
BUD13 homolog
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16
Pleiotropic regulator 1
Cell division cycle 5-like protein
Spliceosome-associated protein CWC15 homolog
Pre-mRNA-splicing factor SPF27
Protein BUD31 homolog
Pre-mRNA-splicing factor RBM22
Peptidyl-prolyl cis-trans isomerase-like 4
Pre-mRNA-splicing factor CWC22 homolog
Crooked neck-like protein 1
SNW domain-containing protein 1
E3 ubiquitin-protein ligase RNF113A
Pre-mRNA-processing-splicing factor 8
116 kDa U5 small nuclear ribonucleoprotein component
U5 small nuclear ribonucleoprotein 200 kDa helicase
U5 small nuclear ribonucleoprotein 40 kDa protein
Peptidyl-prolyl cis-trans isomerase-like 1
Serine/arginine repetitive matrix protein 2
U2 small nuclear ribonucleoprotein A'
U2 small nuclear ribonucleoprotein B''
Pre-mRNA-splicing factor ISY1 homolog
RING-type E3 ubiquitin-protein ligase PPIL2
Peptidyl-prolyl cis-trans isomerase E
Pre-mRNA-processing factor 17
RNA helicase aquarius
Pre-mRNA-splicing factor SYF1
