› 8cit

X-ray diffraction
2.54Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150637 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Moesin Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 347 amino acids
Theoretical weight: 41.19 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P26038 (Residues: 1-346; Coverage: 60%)
Gene name: MSN
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P21
Unit cell:
a: 72.704Å b: 74.049Å c: 115.075Å
α: 90° β: 95.63° γ: 90°
R-values:
R R work R free
0.246 0.244 0.288
Expression system: Escherichia coli BL21

Quick links

Citations

1 review citation

Fused Tetrahydroquinolines Are Interfering with Your Assay.
Bashore et al. (2023)

2 mentions without citation

Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease.
Du et al. (2023)
1 more