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› 8csw

Electron Microscopy
2.5Å resolution

Local refinement of protein 4.2 in Class 2 of erythrocyte ankyrin-1 complex

Released:
DOI: 10.2210/pdb8csw/pdb
PDB entry 8csw coloured by chain, front view.
PDB entry 8csw coloured by chain, side view.
PDB entry 8csw coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Architecture of the human erythrocyte ankyrin-1 complex.
Vallese F, Kim K, Yen LY, Johnston JD, Noble AJ, Calì T, Clarke OB
Nat Struct Mol Biol 29 706-718 (2022)
PMID: 35835865
Related structures: EMD-26973

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147729 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein 4.2 Chain: X
Molecule details ›
Chain: X
Length: 691 amino acids
Theoretical weight: 77.1 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P16452 (Residues: 1-691; Coverage: 100%)
Gene names: E42P, EPB42
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 2.5Å
Relevant EMDB volumes: EMD-26973

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Citations

7 review citations

Bridging structural and cell biology with cryo-electron microscopy.
Nogales et al. (2024)
6 more

2 mentions without citation

Architecture of the human erythrocyte ankyrin-1 complex.
Vallese et al. (2022)
1 more