› 8dtc

X-ray diffraction
2.25Å resolution

Crystal Structure of Glucokinase with bound glucose from Acanthamoeba castellanii

Released:
DOI: 10.2210/pdb8dtc/pdb
PDB entry 8dtc coloured by chain, front view.
PDB entry 8dtc coloured by chain, side view.
PDB entry 8dtc coloured by chain, top view.
Source organism: Acanthamoeba castellanii
Entry authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-125867 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glucokinase Chains: A, B
Molecule details ›
Chains: A, B
Length: 398 amino acids
Theoretical weight: 43.95 KDa
Source organism: Acanthamoeba castellanii
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: L8GT25 (Residues: 2-176, 177-352; Coverage: 100%)
Gene name: ACA1_177380
Sequence domains: Glucokinase

Ligands and Environments

3 bound ligands:
Ligand BGC 4 x BGC
Ligand SO4 2 x SO4
Ligand EDO 2 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Spacegroup: P21
Unit cell:
a: 114.99Å b: 52.79Å c: 118.35Å
α: 90° β: 118.62° γ: 90°
R-values:
R R work R free
0.17 0.169 0.201
Expression system: Escherichia coli BL21(DE3)

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