8dwr

X-ray diffraction
2.1Å resolution

Crystal structure of the L333V variant of catalase-peroxidase from Mycobacterium tuberculosis

Released:
Model geometry
Fit model/data

Function and Biology Details

Reaction catalysed:
2 H(2)O(2) = O(2) + 2 H(2)O
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161625 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Catalase-peroxidase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 746 amino acids
Theoretical weight: 81.53 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:
  • Canonical: P9WIE5 (Residues: 2-740; Coverage: 100%)
Gene names: MTCY180.10, Rv1908c, katG
Sequence domains: Peroxidase

Ligands and Environments


Cofactor: Ligand HEM 4 x HEM
3 bound ligands:
1 modified residue:

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P21
Unit cell:
a: 82.671Å b: 150.817Å c: 127.037Å
α: 90° β: 90.45° γ: 90°
R-values:
R R work R free
0.181 0.181 0.226
Expression system: Escherichia coli