› 8esc

Electron Microscopy
3.1Å resolution

Structure of the Yeast NuA4 Histone Acetyltransferase Complex

Released:
DOI: 10.2210/pdb8esc/pdb
PDB entry 8esc coloured by chain, front view.
PDB entry 8esc coloured by chain, side view.
PDB entry 8esc coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Structure and flexibility of the yeast NuA4 histone acetyltransferase complex.
Zukin SA, Marunde MR, Popova IK, Soczek KM, Nogales E, Patel AB
OpenAccess logo Elife 11 (2022)
PMID: 36263929
Related structures: EMD-28575

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-153734 (preferred)
Entry contents:
6 distinct polypeptide molecules
Macromolecules (6 distinct):
SAGA complex/NuA4 acetyltransferase complex subunit TRA1 Chain: Z
Molecule details ›
Chain: Z
Length: 3744 amino acids
Theoretical weight: 433.68 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P38811 (Residues: 1-3744; Coverage: 100%)
Gene names: TRA1, YHR099W
Sequence domains:
Actin-related protein 4 Chain: R
Molecule details ›
Chain: R
Length: 489 amino acids
Theoretical weight: 54.89 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P80428 (Residues: 1-489; Coverage: 100%)
Gene names: ACT3, ARP4, J1012, YJL081C
Sequence domains: Actin
Actin Chain: A
Enhancer of polycomb-like protein 1 Chain: P
Chromatin modification-related protein EAF1 Chain: E
SWR1-complex protein 4 Chain: S

Ligands and Environments

2 bound ligands:
Ligand ATP 1 x ATP
Ligand MG 2 x MG
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 3.1Å
Relevant EMDB volumes: EMD-28575

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Citations

1 review citation

Envisioning a role for nuclear actin in prophase I spermatocytes.
Petrusová et al. (2023)
4 other articles