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8fua

X-ray diffraction
1.9Å resolution

Crystal structure of mouse Importin alpha in complex with Hendra virus matrix protein NLS1

Released:
Model geometry
Fit model/data

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-271882 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Importin subunit alpha-1 Chain: A
Molecule details ›
Chain: A
Length: 510 amino acids
Theoretical weight: 55.27 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P52293 (Residues: 70-529; Coverage: 87%)
Gene names: Kpna2, Rch1
Sequence domains:
Matrix protein Chains: B, C
Molecule details ›
Chains: B, C
Length: 20 amino acids
Theoretical weight: 2.14 KDa
Source organism: Hendra virus horse/Australia/Hendra/1994
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O89341 (Residues: 80-99; Coverage: 6%)
Gene name: M

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P212121
Unit cell:
a: 78.488Å b: 89.859Å c: 99.829Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.174 0.173 0.19
Expression system: Escherichia coli BL21(DE3)