› 8g4j

X-ray diffraction
2.35Å resolution

Crystal structure of Cavia porcellus (guinea pig) importin-alpha 1 in cargo-free state

Released:
DOI: 10.2210/pdb8g4j/pdb
Model geometry
Fit model/data
PDB entry 8g4j coloured by chain, front view.
PDB entry 8g4j coloured by chain, side view.
PDB entry 8g4j coloured by chain, top view.
Source organism: Cavia porcellus
Entry authors: Hawker JE, Roby JA, Stewart M, Forwood JK

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-124710 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Importin subunit alpha Chains: A, B
Molecule details ›
Chains: A, B
Length: 423 amino acids
Theoretical weight: 45.96 KDa
Source organism: Cavia porcellus
Expression system: Escherichia coli
UniProt:
  • Canonical: H0VVB1 (Residues: 75-497; Coverage: 80%)
Gene name: KPNA2
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P4212
Unit cell:
a: 184.169Å b: 184.169Å c: 57.61Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.216 0.215 0.235
Expression system: Escherichia coli

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