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› 8igi

X-ray diffraction
1.84Å resolution

Crystal structure of HP1526 (XthA)- a base excision DNA repair protein in Helicobacter pylori

Released:
DOI: 10.2210/pdb8igi/pdb
Model geometry
Fit model/data
PDB entry 8igi coloured by chain, front view.
PDB entry 8igi coloured by chain, side view.
PDB entry 8igi coloured by chain, top view.
Source organism: Helicobacter pylori 26695
Primary publication:
Crystal structure of the apurinic/apyrimidinic endonuclease XthA (HP1526 protein) from Helicobacter pylori.
Dinh T, Dao O, Killivalavan A, Ngo D, Lee KH
Biochem Biophys Res Commun 663 8-15 (2023)
PMID: 37116395

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-271636 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Endonuclease/exonuclease/phosphatase domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 251 amino acids
Theoretical weight: 29.51 KDa
Source organism: Helicobacter pylori 26695
Expression system: Escherichia coli
UniProt:
  • Canonical: O26054 (Residues: 1-250; Coverage: 100%)
Gene name: HP_1526
Sequence domains: Endonuclease/Exonuclease/phosphatase family

Ligands and Environments

2 bound ligands:
Ligand MN 2 x MN
Ligand BU2 2 x BU2
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: PHOTON FACTORY BEAMLINE AR-NW12A
Spacegroup: P212121
Unit cell:
a: 72.096Å b: 71.909Å c: 108.033Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.168 0.166 0.196
Expression system: Escherichia coli

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