We've built a new version of this page with an interactive 3D viewer. Try it out in beta and help us improve:

› 8igt

X-ray diffraction
1.56Å resolution

Crystal Structure of Intracellular B30.2 Domain of BTN2A1

Released:
DOI: 10.2210/pdb8igt/pdb
Model geometry
Fit model/data
PDB entry 8igt coloured by chain, front view.
PDB entry 8igt coloured by chain, side view.
PDB entry 8igt coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate Vγ9Vδ2 T cells.
Yuan L, Ma X, Yang Y, Qu Y, Li X, Zhu X, Ma W, Duan J, Xue J, Yang H, Huang JW, Yi S, Zhang M, Cai N, Zhang L, Ding Q, Lai K, Liu C, Zhang L, Liu X, Yao Y, Zhou S, Li X, Shen P, Chang Q, Malwal SR, He Y, Li W, Chen C, Chen CC, Oldfield E, Guo RT, Zhang Y
OpenAccess logo Nature (2023)
PMID: 37674084

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-274989 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Butyrophilin subfamily 2 member A1 Chain: A
Molecule details ›
Chain: A
Length: 222 amino acids
Theoretical weight: 25.55 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7KYR7 (Residues: 314-314, 316-527; Coverage: 43%)
Gene names: BT2.1, BTF1, BTN2A1
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SSRF BEAMLINE BL17U1
Spacegroup: P21212
Unit cell:
a: 73.957Å b: 78.889Å c: 41.682Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.156 0.155 0.173
Expression system: Escherichia coli

Quick links

Citations

2 review citations

The Role of γδ T-Lymphocytes in Glioblastoma: Current Trends and Future Directions.
Ahmedna et al. (2023)
1 more

1 mention without citation

Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate Vγ9Vδ2 T cells.
Yuan et al. (2023)