› 8qk2

X-ray diffraction
1.95Å resolution

Function and Biology Details

Reaction catalysed: 
A UDP-2-N,3-O-bis((3R)-3-hydroxyacyl)-alpha-D-glucosamine + H(2)O = a lipid X + UMP
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-269877 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
UDP-2,3-diacylglucosamine hydrolase Chain: A
Molecule details ›
Chain: A
Length: 246 amino acids
Theoretical weight: 28.01 KDa
Source organism: Klebsiella pneumoniae
Expression system: Escherichia coli
UniProt:
  • Canonical: A6T5R0 (Residues: 1-240; Coverage: 100%)
Gene names: KPN78578_04700, KPN_00480, lpxH
Sequence domains: Calcineurin-like phosphoesterase

Ligands and Environments

2 bound ligands:
Ligand MN 2 x MN
Ligand VTF 1 x VTF
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P6122
Unit cell:
a: 60.204Å b: 60.204Å c: 286.779Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.225 0.224 0.253
Expression system: Escherichia coli

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