Function and Biology Details
Reaction catalysed:
RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Influenza RNA-dependent RNA polymerase subunit PB1
- Protein A, Ig-binding domain
- Immunoglobulin/albumin-binding domain superfamily
- PB2, C-terminal
- Influenza RNA polymerase PB2, C-terminal domain
- Influenza RNA polymerase PB2, sixth domain
- Influenza RNA polymerase PB2, CAP binding domain
- Polymerase basic protein 2, helical domain
12 more domains
Structure analysis Details
Assembly composition:
hetero heptamer (preferred)
PDBe Complex ID:
PDB-CPX-269864 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Polymerase acidic protein
Molecule details ›
Chains: A, D
Length: 716 amino acids
Theoretical weight: 82.6 KDa
Source organism: Influenza A virus
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Influenza RNA-dependent RNA polymerase subunit PA
Length: 716 amino acids
Theoretical weight: 82.6 KDa
Source organism: Influenza A virus
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
A5Z236 (Residues: 1-713; Coverage: 100%)
Sequence domains: Influenza RNA-dependent RNA polymerase subunit PA
RNA-directed RNA polymerase catalytic subunit
Molecule details ›
Chains: B, E
Length: 757 amino acids
Theoretical weight: 86.62 KDa
Source organism: Influenza A virus
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Influenza RNA-dependent RNA polymerase subunit PB1
Length: 757 amino acids
Theoretical weight: 86.62 KDa
Source organism: Influenza A virus
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: A5Z231 (Residues: 1-754; Coverage: 100%)
Sequence domains: Influenza RNA-dependent RNA polymerase subunit PB1
Polymerase basic protein 2
Acidic leucine-rich nuclear phosphoprotein 32 family member B
