› 8rcq

X-ray diffraction
3.8Å resolution

Structural flexibility of Nucleoprotein of the Toscana virus in the presence of a nanobody.

Released:
DOI: 10.2210/pdb8rcq/pdb
Model geometry
Fit model/data
PDB entry 8rcq coloured by chain, front view.
PDB entry 8rcq coloured by chain, side view.
PDB entry 8rcq coloured by chain, top view.
Source organisms:
Primary publication:
Structural flexibility of Toscana virus nucleoprotein in the presence of a single-chain camelid antibody.
Papageorgiou N, Baklouti A, Lichière J, Desmyter A, Canard B, Coutard B, Ferron F
Acta Crystallogr D Struct Biol (2024)
PMID: 38265877

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-239379 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Nucleoprotein Chain: A
Molecule details ›
Chain: A
Length: 253 amino acids
Theoretical weight: 27.67 KDa
Source organism: Toscana virus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P21701 (Residues: 2-253; Coverage: 100%)
Gene name: N
Sequence domains: Tenuivirus/Phlebovirus nucleocapsid protein
VHH Chain: B
Molecule details ›
Chain: B
Length: 137 amino acids
Theoretical weight: 14.95 KDa
Source organism: Lama glama
Expression system: Escherichia coli BL21(DE3)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P41212
Unit cell:
a: 54.755Å b: 54.755Å c: 380.647Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.3 0.3 0.35
Expression system: Escherichia coli BL21(DE3)

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