› 8rdh

X-ray diffraction
2.4Å resolution

Crystal structure of UDP-galactose 4-epimerase from Pyrococcus horikoshii with bound NAD and GDP-L-fucose

Released:
DOI: 10.2210/pdb8rdh/pdb
Model geometry
Fit model/data
PDB entry 8rdh coloured by chain, front view.
PDB entry 8rdh coloured by chain, side view.
PDB entry 8rdh coloured by chain, top view.
Source organism: Pyrococcus horikoshii
Entry authors: Thunnissen AMWH, Alvarez Quispe C, Desmet T

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-283832 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NAD-dependent epimerase/dehydratase domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 326 amino acids
Theoretical weight: 36.71 KDa
Source organism: Pyrococcus horikoshii
Expression system: Escherichia coli
UniProt:
  • Canonical: O73960 (Residues: 1-318; Coverage: 100%)
Gene name: PH0378
Sequence domains: NAD dependent epimerase/dehydratase family

Ligands and Environments

2 bound ligands:
Ligand NAD 2 x NAD
Ligand GFB 2 x GFB
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: ESRF BEAMLINE MASSIF-1
Spacegroup: P212121
Unit cell:
a: 57.331Å b: 97.262Å c: 117.252Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.188 0.245
Expression system: Escherichia coli

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