› 8spa

Electron Microscopy
3Å resolution

Structural insights into cellular control of the human CPEB3 prion, functionally regulated by a labile-amyloid-forming segment

Released:
DOI: 10.2210/pdb8spa/pdb
PDB entry 8spa coloured by chain, front view.
PDB entry 8spa coloured by chain, side view.
PDB entry 8spa coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Flores MD, Sawaya MR, Boyer DR, Zink S, Fioriti L, Rodriguez JA
Related structures: EMD-40677

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-275164 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytoplasmic polyadenylation element-binding protein 3 Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 49 amino acids
Theoretical weight: 5.28 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: Q8NE35 (Residues: 103-151; Coverage: 7%)
Gene names: CPEB3, KIAA0940

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 3Å
Relevant EMDB volumes: EMD-40677
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'

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