› 8wcg

X-ray diffraction
2.6Å resolution

Crystal structure of SARS-CoV-1 RBD in complex with nanobody aSR29 and aSR347

Released:
DOI: 10.2210/pdb8wcg/pdb
Model geometry
Fit model/data
PDB entry 8wcg coloured by chain, front view.
PDB entry 8wcg coloured by chain, side view.
PDB entry 8wcg coloured by chain, top view.
Source organisms:
Entry authors: Zeng WH, Ma H, Jin TC

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-273933 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Spike protein S1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 197 amino acids
Theoretical weight: 22.19 KDa
Source organism: Severe acute respiratory syndrome coronavirus
Expression system: Homo sapiens
UniProt:
  • Canonical: P59594 (Residues: 320-516; Coverage: 16%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
aSR29 nanobody Chains: C, D
Molecule details ›
Chains: C, D
Length: 127 amino acids
Theoretical weight: 14.08 KDa
Source organism: Vicugna pacos
Expression system: Homo sapiens
aSR347 nanobody Chains: E, b

Ligands and Environments

1 bound ligand:
Ligand NAG 2 x NAG
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SSRF BEAMLINE BL10U2
Spacegroup: P212121
Unit cell:
a: 76.852Å b: 134.679Å c: 136.688Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.235 0.232 0.279
Expression system: Homo sapiens

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