› 8xml

Electron Microscopy
2.58Å resolution

Cryo-EM structure of the Apo CCR8-Gi complex

Released:
DOI: 10.2210/pdb8xml/pdb
PDB entry 8xml coloured by chain, front view.
PDB entry 8xml coloured by chain, side view.
PDB entry 8xml coloured by chain, top view.
Source organisms:
Entry authors: Peng Q, Jiang HH, Cheng XY, Li J, Zhang J
Related structures: EMD-38481

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-283472 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
C-C chemokine receptor type 8; Soluble cytochrome b562 Chain: R
Molecule details ›
Chain: R
Length: 461 amino acids
Theoretical weight: 52.69 KDa
Source organisms: Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P0ABE7 (Residues: 23-127; Coverage: 99%)
  • Canonical: P51685 (Residues: 1-355; Coverage: 100%)
Gene names: CCR8, CKRL1, CMKBR8, CMKBRL2, cybC
Sequence domains:
Guanine nucleotide-binding protein G(i) subunit alpha-1 Chain: A
Molecule details ›
Chain: A
Length: 354 amino acids
Theoretical weight: 40.45 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P63096 (Residues: 1-354; Coverage: 100%)
Gene name: GNAI1
Sequence domains: G-protein alpha subunit
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Chain: B
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Chain: G
scFv16 Chain: S

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 2.58Å
Relevant EMDB volumes: EMD-38481
Expression system: Spodoptera frugiperda

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