› 8yt4

Electron Microscopy
1.42Å resolution

Structure of Aquifex aeolicus Lumazine Synthase by Cryo-Electron Microscopy to 1.42 Angstrom Resolution

Released:
DOI: 10.2210/pdb8yt4/pdb
PDB entry 8yt4 coloured by chain, front view.
PDB entry 8yt4 coloured by chain, side view.
PDB entry 8yt4 coloured by chain, top view.
Source organism: Aquifex aeolicus
Primary publication:
Structure of Aquifex aeolicus lumazine synthase by cryo-electron microscopy to 1.42 Å resolution.
Savva CG, Sobhy MA, De Biasio A, Hamdan SM
IUCrJ (2024)
PMID: 38965901
Related structures: EMD-39478

Function and Biology Details

Reaction catalysed: 
1-deoxy-L-glycero-tetrulose 4-phosphate + 5-amino-6-(D-ribitylamino)uracil = 6,7-dimethyl-8-(D-ribityl)lumazine + 2 H(2)O + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo 60-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130334 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
6,7-dimethyl-8-ribityllumazine synthase Chain: A
Molecule details ›
Chain: A
Length: 162 amino acids
Theoretical weight: 17.77 KDa
Source organism: Aquifex aeolicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O66529 (Residues: 1-154; Coverage: 100%)
Gene names: aq_132, ribH
Sequence domains: 6,7-dimethyl-8-ribityllumazine synthase

Ligands and Environments

1 bound ligand:
Ligand PO4 1 x PO4
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 1.42Å
Relevant EMDB volumes: EMD-39478
Expression system: Escherichia coli BL21(DE3)

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