› 9fr2

X-ray diffraction
1.6Å resolution

CDK2 in complex with WEIZ-WX-04-001

Released:
DOI: 10.2210/pdb9fr2/pdb
Model geometry
Fit model/data
PDB entry 9fr2 coloured by chain, front view.
PDB entry 9fr2 coloured by chain, side view.
PDB entry 9fr2 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Wang GQ, Liu YH, Knapp S, Structural Genomics Consortium (SGC)

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150313 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cyclin-dependent kinase 2 Chain: A
Molecule details ›
Chain: A
Length: 299 amino acids
Theoretical weight: 34.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P24941 (Residues: 1-298; Coverage: 100%)
Gene names: CDK2, CDKN2
Sequence domains: Protein kinase domain

Ligands and Environments

1 bound ligand:
Ligand A1IE9 1 x A1IE9
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P212121
Unit cell:
a: 53.38Å b: 71.949Å c: 71.995Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.188 0.186 0.223
Expression system: Escherichia coli BL21(DE3)

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