EMD-20189
Cryo-EM structure of vaccine-elicited antibody 0PV-a.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122
EMD-20189
Single-particle4.3 Å
Deposition: 02/05/2019Map released: 24/07/2019
Last modified: 29/07/2020
Sample Organism:
Homo sapiens,
Human immunodeficiency virus 1
Sample: HIV-1 Env BG505 DS-SOSIP and antibodies 0PV-a.01, VRC03 and PGT122
Fitted models: 6osy
Deposition Authors: Gorman J, Kwong PD
Sample: HIV-1 Env BG505 DS-SOSIP and antibodies 0PV-a.01, VRC03 and PGT122
Fitted models: 6osy
Deposition Authors: Gorman J, Kwong PD
Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Kong R,
Duan H 
,
Sheng Z,
Xu K,
Acharya P ,
Chen X,
Cheng C,
Dingens AS,
Gorman J,
Sastry M,
Shen CH,
Zhang B,
Zhou T,
Chuang GY,
Chao CW,
Gu Y,
Jafari AJ,
Louder MK,
O'Dell S,
Rowshan AP,
Viox EG,
Wang Y,
Choi CW,
Corcoran MM ,
Corrigan AR ,
Dandey VP,
Eng ET ,
Geng H,
Foulds KE,
Guo Y ,
Kwon YD,
Lin B,
Liu K,
Mason RD,
Nason MC,
Ohr TY,
Ou L,
Rawi R,
Sarfo EK ,
Schon A,
Todd JP,
Wang S,
Wei H,
Wu W,
Mullikin JC,
Bailer RT,
Doria-Rose NA,
Karlsson Hedestam GB,
Scorpio DG,
Overbaugh J,
Bloom JD,
Carragher B,
Potter CS,
Shapiro L,
Kwong PD,
Mascola JR
(2019) Cell , 178 , 567 - 584.e19
,
Sheng Z,
Xu K,
Acharya P ,
Chen X,
Cheng C,
Dingens AS,
Gorman J,
Sastry M,
Shen CH,
Zhang B,
Zhou T,
Chuang GY,
Chao CW,
Gu Y,
Jafari AJ,
Louder MK,
O'Dell S,
Rowshan AP,
Viox EG,
Wang Y,
Choi CW,
Corcoran MM ,
Corrigan AR ,
Dandey VP,
Eng ET ,
Geng H,
Foulds KE,
Guo Y ,
Kwon YD,
Lin B,
Liu K,
Mason RD,
Nason MC,
Ohr TY,
Ou L,
Rawi R,
Sarfo EK ,
Schon A,
Todd JP,
Wang S,
Wei H,
Wu W,
Mullikin JC,
Bailer RT,
Doria-Rose NA,
Karlsson Hedestam GB,
Scorpio DG,
Overbaugh J,
Bloom JD,
Carragher B,
Potter CS,
Shapiro L,
Kwong PD,
Mascola JR
(2019) Cell , 178 , 567 - 584.e19